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Taltobulin trifluoroacetate (HTI-286 trifluoroacetate) |...
来自 : www.medchemexpress.cn/Taltobul
发布时间:2021-03-24
Taltobulin (HTI-286; 1.6 mg/kg i.v.) inhibits the growth of human tumor xenografts (e.g., HCT-15, DLD-1, MX-1W, and KB-8-5) in athymic nu/nu female mice[1].
Taltobulin (HTI-286; 3 mg/kg; p.o. gavage) inhibits growth by 97.3 % and 82% in athymic nu/nu female mice with Lox melanoma xenografts and KB-3-1 epidermoid xenograft model, respectively[1].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Taltobulin trifluoroacetate (HTI-286 trifluoroacetate) 是一种合成的三肽半胱氨酸类似物,Taltobulin 是一种有效的抗微管剂 (antimicrotubule),可在体内外规避 P...Taltobulin | HTI-286 | SPA-110 | HTI286 | HTI 286 | SPA110 | SPA 110 | Microtubule/Tubulin | ADC Cytotoxin | Apoptosis | Inhibitor | inhibitor | inhibitTaltobulin trifluoroacetate (HTI-286 trifluoroacetate) 是一种合成的三肽半胱氨酸类似物,Taltobulin 是一种有效的抗微管剂 (antimicrotubule),可在体内外规避 P-糖蛋白介导的耐药性。Taltobulin trifluoroacetate 抑制纯化的微管蛋白聚合,破坏细胞中的微管组织,并诱导有丝分裂停滞以及凋亡 (apoptosis)。- 高纯度,全球文献引用。Taltobulin trifluoroacetate (HTI
本文链接: http://altochem.immuno-online.com/view-695282.html
发布于 : 2021-03-24
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